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Selective serotonin reuptake inhibitors (SSRIs) are primarily used in treating anxiety disorders as a long-term management strategy. They work by increasing the levels of serotonin in the brain, which can help improve mood and reduce anxiety over time. Unlike some medications that provide immediate relief, such as benzodiazepines, SSRIs take several weeks to produce their full therapeutic effect, making them suitable for sustained treatment rather than immediate relief.

The long-term use of SSRIs helps to stabilize mood and anxiety levels, addressing the underlying neurochemical imbalances associated with various anxiety disorders. They are often considered first-line treatment options due to their efficacy and favorable side-effect profile compared to other anxiolytics.

Other options, such as immediate relaxation or sedative effects, do not describe the role of SSRIs accurately. SSRIs are not sedatives; instead, they can improve anxiety symptoms without the immediate tranquilizing effects. They are also not exclusively prescribed for major depressive disorder, as they have shown effectiveness in various conditions, including generalized anxiety disorder, panic disorder, social anxiety disorder, and obsessive-compulsive disorder. This versatility underscores their significance in long-term anxiety management.